25-1201m Opioid Interactions: Potentiator Drugs That Increase the Risk of Overdose
Date: 11/21/25
Know which medications may intensify opioid effects
This information applies to Ancillary Providers, Community Supports (CS) Providers, Enhanced Care Management (ECM) Providers, and Behavioral Health Providers.
For Medi-Cal, this information applies to Amador, Calaveras, Inyo, Los Angeles, Molina, Mono, Sacramento, San Joaquin, Stanislaus, Tulare and Tuolumne counties.