25-1086 New Policy Expands Access to Hepatitis C Treatment
Date: 10/27/25
Full-course dispensing now allowed as of October 1, 2025
Effective October 1, 2025, the California Department of Health Care Services (DHCS) has removed the 28-day supply limitation for Hepatitis C treatments under Medi-Cal RX. Physicians and other providers may now dispense up to a 12-week supply per fill -- supporting uninterrupted care and better health outcomes.
Why this matters
This policy change is backed by strong clinical evidence and strives to reduce barriers to care for Medi-Cal members.
- High completion rates among Medi-Cal members
- Glecaprevir/Pibrentasvir: 89% completion rate
- Sofosbuvir/Velpatasvir: 83% completion rate
Note: These are just some of the drugs affected by this policy change.
- MINMON study confirms safety and effectiveness
- 89% of participants took 100% of their medication over 12 weeks
- 95% achieved sustained virologic response (SVR)
- Expanded dispensing supports justice-involved populations
- Enables treatment continuity for individuals transitioning from incarceration to the community
- Reduces risk of treatment interruption and need for complex regimens
What providers need to know
- Full-course dispensing is now permitted for eligible Hepatitis C treatments. Please visit Contract Drugs List
- This change aligns with DHCS efforts to improve access and outcomes for vulnerable populations
Questions?
For questions about dispensing changes or the applicable treatments, please contact Medi-Cal RX.
Additional information
Providers are encouraged to access the provider portal for real-time information, including eligibility verification, claims status, prior authorization status, plan summaries, and more.
If you have questions regarding the information contained in this update, contact Community Health Plan of Imperial Valley at 833-236-4141.
This information applies to Physicians and Participating Physician Groups (PPGs).
This information applies to Medi-Cal in Imperial County.